A Clinico-Pharmacological Study on trans-4- (2-Amino-3, 5 dibrornobenzylamino) cyclohexanol hydrochloride
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چکیده
منابع مشابه
Effect of 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)-3-nitrosourea hydrochloride on experimental brain tumors.
permits easy passage across the blood-brain barrier. Others have argued that since brain tumors do not possess a blood brain barrier, the lipid solubility of the nitrosoureas can play no robein their therapeutic effectiveness. We have tested ACNU, a water-soluble nitrosourea, for its chemotherapeutic effect in several animal brain tumor models and have compared ACNU to other more lipid-soluble ...
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Insofar as one of the fundamenta l object ives of organic synthesis is the const ruct ion of complex molecules from simpler ones, the impor tance of synthet ic efficiency becomes immedia tely apparen t and has been well-recognized.1 The increase in molecula r complexity2 tha t necessar ily accompanies the course of a synthesis provides a guide (and a measure) of synthet ic efficiency. As a goal...
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A new antimicrobial nitrofuran designated SQ 18,506 showed some therapeutic activity when administered orally to mice infected with Escherichia coli, Salmonella schottmuelleri, Shigella flexneri, or Klebsiella pneumoniae. Animals infected parenterally with Streptococcus pyogenes, Proteus mirabilis, Mycobacterium tuberculosis, and Candida albicans, or topically with Trichophyton mentagrophytes, ...
متن کاملEffect of 1-(4-Amino-2-methyl-5-pyrimidinyl)methyl-342-chloroethyl}. 3-nitrosourea Hydrochloride on Experimental Brain Tumors'
permits easy passage across the blood-brain barrier. Others have argued that since brain tumors do not possess a blood brain barrier, the lipid solubility of the nitrosoureas can play no robein their therapeutic effectiveness. We have tested ACNU, a water-soluble nitrosourea, for its chemotherapeutic effect in several animal brain tumor models and have compared ACNU to other more lipid-soluble ...
متن کاملtrans-Bis[4-amino-3,5-bis(2-pyridyl)-4H-1,2,4-triazole-κN 3]diaquacobalt(II) bis(3-carboxy-5-nitrobenzoate)
The title complex, [Co(C(12)H(10)N(6))(2)(H(2)O)(2)](C(8)H(4)NO(6))(2), is composed of a mononuclear cobalt(II) cation and two 3-carb-oxy-5-nitro-benzoate anions for charge balance. In the cation, the Co(II) atom is six-coordinated in a distorted octa-hedral geometry. It bonds to two O atoms of two water mol-ecules, and two pairs of N atoms from two 4-amino-3,5-bis-(2-pyrid-yl)-4H-1,2,4-triazol...
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ژورنال
عنوان ژورنال: Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics
سال: 1977
ISSN: 1882-8272,0388-1601
DOI: 10.3999/jscpt.8.25